Written by Pam MS, NCSP | Fact checked by Psychology Dictionary staff 

noun. a brain malformation wherein the convolutions of the cerebral cortex are irregularly thick. It is generally joined by a lessening of the fissures between the gyri. Commonly referred to as macrogyria.

PACHYGYRIA: "It appears as though pachygyria is the cause of Brent's seizures- epilepsy has not been ruled out yet either."

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