Written by Pam MS, NCSP | Fact checked by Psychology Dictionary staff 

noun. the Datura innoxia plant, belonging to the nightshade family and tightly correlated to jimsonweed, which is comprised of many alkaloids with forceful anticholinergic impacts.

TOLOACHE: "The toloache has been utilized by many native people of Central and North America for adolescent rituals and religious ceremonies."

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