Written by Pam MS, NCSP | Fact checked by Psychology Dictionary staff 

noun. 1. a vulnerability to forming a disorder or illness, the actual growth of which is started by the interaction of particular biological, psychological, or climate-based aspects. 2. with regard to genetics, any genetic aspect which, rendered the required conditions, will lead to the growth of a particular attribute or illness.

PREDISPOSITION: "A child's predisposition to bipolar disorder, of any type, is extremely high whenever both parents are affected too."

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