n. the first-two major cancer genes associated with a person's susceptibility to breast and ovarian cancer. In women with mutations in one of these two genes, the risk of breast cancer is at 56-85%. A mutation in the second gene also increases the rate of male breast cancer, although the figure runs low at 5%.

BRCA1 AND BRCA2: "Thanks to the initial discovery of BRCA1 and BRCA2, cancer screening and testing was made possible."
Cite this page: N., Pam M.S., "BRCA1 AND BRCA2," in, April 7, 2013, (accessed July 27, 2021).