n. a hypothesis which suggests that a deficiency in catecholamines, such as neurotransmitters in the brain, could cause a chemical imbalance in the body. This imbalance contributes to the onset of mental and affective disorders, one of which would be depression.

CATECHOLAMINE HYPOTHESIS: "True to the catecholamine hypothesis, dopamine and norepinephrine do tend to exert a certain influence in affective disorders like depression, for instance."
Cite this page: N., Pam M.S., "CATECHOLAMINE HYPOTHESIS," in, April 7, 2013, (accessed October 18, 2021).