DOWN-REGULATION By N., Sam M.S. - 14 The decrease in the number of receptor molecules in an area. See up-regulation. DOWN-REGULATION: "Down regulation means there are less receptor molecules in the area." Related Psychology Terms ALLOSTERIC MODULATION MAOIS HEARING (AUDITION) NMDA RECEPTOR IONOTROPIC RECEPTOR ENURESIS (Bed-wetting) ADOLESCENCE (Theories) ABSOLUTE THRESHOLD ELECTROSHOCK THERAPY (Elec- troconvulsive Therapy; EST, ECT) ANABOLISM Cite this page: N., Sam M.S., "DOWN-REGULATION," in PsychologyDictionary.org, April 7, 2013, https://psychologydictionary.org/down-regulation/ (accessed December 6, 2022).