noun. The capacity for a drug, frequently a depressant to the central nervous system, to generate the decreased impacts of another drug of the like kind whenever attitude tolerance for the impacts of the latter compound have formed.

CROSS-TOLERANCE: "Cross-tolerance is what aids in decreasing symptoms of withdrawal for alcoholics by the administration of other drugs which cause similar symptoms as does alcohol."
Cite this page: N., Pam M.S., "CROSS-TOLERANCE," in, April 7, 2013, (accessed October 16, 2021).