EPENA By N., Pam M.S. - April 7, 2013 Hallucinogenic snuff made from the bark of South American trees of the Virola genus. The active ingredient is similar to LSD. EPENA: "Epena is a snuff made in South America with similar properties to LSD." Related Psychology Terms AYAHUASCA BUFOTENIN BUFOTENIN GUARANINE, PSILOCIN TOBACCO METHYLXANTHINES NUTMEG MESCALINE KOLA NUT (COLA NUT) Cite this page: N., Pam M.S., "EPENA," in PsychologyDictionary.org, April 7, 2013, https://psychologydictionary.org/epena/ (accessed June 23, 2021).