noun. a chemical response wherein a compound mixes with oxygen or wherein electrons are lost. With regard to drug metabolism, is it a typical mechanism of Phase I metabolism, wherein drugs are made to be more polar by adding an oxygen atom, frequently through the action of cytochrome P450 enzymes.

OXIDATION: "Oxidation and reduction often go hand-in-hand."
Cite this page: N., Pam M.S., "OXIDATION," in PsychologyDictionary.org, April 7, 2013, https://psychologydictionary.org/oxidation/ (accessed September 27, 2021).