the condition of someone who has repeatedly ingested a drug and will encounter undesirable physiological symptoms if they discontinue use of the drug. In the DSM-IV-TR, substance dependence with physical dependence is identified and a diagnosis is rendered if there is proof of tolerance or withdrawal.

PHYSICAL DEPENDENCE: "Your physical dependence on the drug is quite obvious- nothing you can will convince us not to send you to rehab."
Cite this page: N., Pam M.S., "PHYSICAL DEPENDENCE," in, April 7, 2013, (accessed October 16, 2021).