REFRACTORY By N., Pam M.S. - April 28, 2013 Any disease or disability that resists treatment or fails to react to a prior efficacious therapy. In, neurophysiology, a neuron or muscle cell which cannot react to stimuli. REFRACTORY: "The teenager suffered from refractory acne." Related Psychology Terms REFRACTORY MENTAL ILLNESS RECOVERY TIME REFRACTORY PERIOD DISCHARGE END PLATE POSITIVE AFTERPOTENTIAL BIPOLAR CELL NEUROMUSCULAR JUNCTION APLYSIA POSTSYNAPTIC RECEPTOR Cite this page: N., Pam M.S., "REFRACTORY," in PsychologyDictionary.org, April 28, 2013, https://psychologydictionary.org/refractory/ (accessed July 16, 2019).