Area of grey matter in the middle brain, called after its dark pigment. It sends dopaminergic neurons to basal ganglia. If these dopamenergic neurons are depleted in this region then symptoms of Parkinson's disease are seen.

SUBSTANTIA NIGRA: "Example: Substantia nigra is very important in study of Parkinson's disease."
Cite this page: N., Pam M.S., "SUBSTANTIA NIGRA," in, April 13, 2013, (accessed May 11, 2021).