noun. a surgical process wherein a disk of bone is excised, generally from the cranium, with a circular tool having a saw-like edge.

TREPHINATION: "Trephination of the skull is thought to be one of the earliest forms of surgery to have existed."
Cite this page: N., Pam M.S., "TREPHINATION," in, April 29, 2013, (accessed July 12, 2020).