Autosomal recessive condition characterized by growth and mental retardation, a beak-like nose, micrognathism, microcephaly, prominent maxilla and eyes, hypertelorism, strabismus, anti-mongoloid slant of palpebral fissures, premature balding, short trunk, variable musculoskeletal changes, linked to defects in chromosome 3. Also known as: Seckel nanism; Virchow-Seckel Syndrome.