noun. a category of vasoconstrictor drugs utilized for the remediation of migraine headache, the prototype of which is sumatriptanoun. Triptans place their therapeutic impact by serving as serotonin-receptor agonists at 5- HTib and 5-HT, receptors, eliciting the constriction of cerebral blood vessels. Triptans ought not to be delivered together with monoamine oxidase inhibitors and ought to be utilized carefully with SSRI's to avoid the possibility of precipitating a serotonin syndrome.
TRIPTANS: "Triptans are widely used, despite some medical evidence supporting some medical professionals' negative opinions of them."