noun. an anticonvulsant drug which is additionally utilized as a mood stabilizer for the remediation of bipolar disorders. Topiramate acts by slowing neurotransmission via blockade of sodium channel; it also apparently reinforces the activity of the neurotransmitter gamma-amino butyric acid and restricts activity at glutamate receptors. Psychomotor slowing and somnolence are common negative impacts. United States brand name: Topamax.
TOPIRAMATE: "I have been taking Topiramate for six months now with positive results."